pi3k/mtor inhibitor-6 — TargetMol Chemicals

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Search Results for " pi3k/mtor inhibitor-6 "

Compounds

Cat No.	Product Name	Synonyms	Targets
T64219	PI3K/mTOR Inhibitor-6
	PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent dual PI3K/mTOR inhibitor that is more stable than gedatolisib in artificial gastric fluid. 10 μM of PI3K/mTOR Inhibitor-6 significantly inhibits the PI3K/Akt/mTOR signalli...
T6732	WYE-687		p38 MAPK , PI3K , Src , mTOR
	WYE-687 is an ATP-competitive and selective inhibitor of mTOR with IC50 of 7 nM; blocks mTORC1/pS6K(T389) and mTORC2/P-AKT(S473) but no effect observed on P-AKT(T308). Selectivity for mTOR is greater than PI3Kα (>100-fol...		p38 MAPK , PI3K , Src , mTOR
T62580	PI3K-IN-37
	PI3K-IN-37 (Example 84.1) is an inhibitor of PI3K α (IC50: 6 nM), PI3K β (IC50: 8 nM) and PI3K δ (IC50: 4 nM). PI3K-IN-37 inhibits mTOR with an IC50 value of 4 nM.
T62545	HDAC-IN-43
	HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82 nM for HDAC 1, 45 nM for HDAC 3, and 24 nM for HDAC 6. HDAC-IN-43 is a weak PI3K/mTOR inhibitor with IC50 values of 3.6 μM for PI3K and 3.7 μM for mTOR. ...
T38263	TBK1/IKKε-IN-4	TBK1/IKKε-IN-4
	TBK1/IKKε-IN-4, a 6-aminopyrazolopyrimidine derivative, serves as a potent, selective inhibitor for TBK1 and IKKε, demonstrating IC50 values of 13 nM and 59 nM, respectively. This compound exhibits significantly reduced ...